Journal of Forensic and Legal Medicine
Volume 16, Issue 7 , Pages 397-399 , October 2009

Positive prostate-specific antigen (PSA) reaction in post-mortem rectal swabs: A cautionary note

  • Philippe Lunetta, PhD (Medical Doctor)

      Affiliations

    • Corresponding Author InformationCorresponding author. Tel.: +358 9 19127473, +358 40 5589892 (GSM); fax: +358 9 19127518.
    • ,
  • Helmuth Sippel, Lic. Phil. (Forensic Chemist)

Received 27 November 2008 ,Revised 15 March 2009 ,Accepted 2 April 2009.

References 

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  2. Simich JP, Morris SL, Klick RL, Rittenhouse-Diakun K. Validation of the use of a commercially available kit for the identification of prostate specific antigen (PSA) in semen stains. J Forensic Sci. 1999;44:1229–1231
  3. Khaldi N, Miras A, Botti K, Benali L, Gromb S. Evaluation of three rapid detection methods for the forensic identification of seminal fluid in rape cases. J Forensic Sci. 2004;49:749–753
  4. Laux DL, Custis SE. Forensic detection of semen III. Detection of PSA using membrane based tests: sensitivity issues with regards to the presence of PSA in other body fluids; 2004. <http://www.mafs.net/pdf/forensicdetectionsemen3.pdf>.
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  7. Saukko P, Knight B. Knight’s forensic pathology. London: Hodder Arnold; 2004;p. 428
  8. Montagna CP. The recovery of seminal components and DNA from the vagina of a homicide victim 34 days postmortem. J Forensic Sci. 1996;41:700–702
  9. Levine B, Titus JM, Moore K, Fowler D. Use of prostate specific antigen in the identification of semen in postmortem cases. Am J Forensic Med Pathol. 2004;25:288–290
  10. Tallthip J. An autopsy report case of rape victim by the application of PSA test kit as a new innovation for sexual assault investigation in Thailand. J Med Assoc Thai. 2007;90:348–351
  11. Seratec Ges. F. Biotechnologie mbH. PSA in body fluids – an overwiew for users of the Seratec PSA semiquant tests. Seratec Ges.f.Biotechnologie GmbH, Rev.1_2006-04, Göttingen, Germany.
  12. Promega Corporation. PowerPlex® Y System Technical Manual # D018, USA; 2003.
  13. Kamoshida S, Tsutsumi Y. Extraprostatic localization of prostatic acid phosphatase and prostate-specific antigen: distribution in cloacogenic glandular epithelium and sex-dependent expression in human anal gland. Hum Pathol. 1990;21:1108–1111
  14. Graves HCB. Nonprostatic sources of protein-specific antigen: a steroid hormone-dependent phenomenon?. Clin Chem. 1995;41:7–9

☆ This report was partly presented as a poster in the 18th International Association of Forensic Sciences meeting 21–25 July 2008.

PII: S1752-928X(09)00051-1

doi: 10.1016/j.jflm.2009.04.002

Journal of Forensic and Legal Medicine
Volume 16, Issue 7 , Pages 397-399 , October 2009

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