Journal of Forensic and Legal Medicine
Volume 16, Issue 4 , Pages 204-211, May 2009

Genetic population analysis of 17 Y-chromosomal STRs in three states (Valle del Cauca, Cauca and Nariño) from Southwestern Colombia

  • Sandra Julieta Ávila, MSc (Professional Forensic Expert)

      Affiliations

    • Grupo de Genética Forense, Instituto Nacional de Medicina Legal y Ciencias Forenses, Calle 7A 12-61 Tercer piso, Bogotá, Colombia
    • Corresponding Author InformationCorresponding author. Tel.: +57 1 4069944/6061106x1314/1328.
    • ,
  • Ignacio. Briceño, MD PhD (Associate Professor)

      Affiliations

    • Instituto de Genética Humana, Facultad de Medicina, Pontificia Universidad Javeriana, Bogotá, Colombia
    • ,
  • Alberto. Gómez, PhD (Professor)

      Affiliations

    • Instituto de Genética Humana, Facultad de Medicina, Pontificia Universidad Javeriana, Bogotá, Colombia

Received 9 November 2007; received in revised form 4 September 2008; accepted 9 December 2008.

Abstract 

Seventeen Y-chromosomal (DYS19, DYS389 I/II, DYS390, DYS391, DYS392, DYS393, DYS438, DYS439, DYS437, DYS448, DYS456, DYS458, DYS635, YGATA-H4 and DYS385a/b) short tandem repeat (STR) polymorphic systems were typed in three South West Colombian populations: Valle (short term for Valle del Cauca), Cauca and Nariño. DYS385a/b showed the highest gene diversity in the three populations. A total of 287 different Y-chromosome haplotypes were observed in the 308 males analyzed, and the haplotype diversity among populations was 0.9977. The most frequent haplotype was observed only three times and only nineteen others were observed two times. The highest gene diversity was found in Valle and the lowest in Cauca. Analysis of molecular variance (AMOVA) revealed that variation is mainly within populations (99.1%) in agreement with previous results in European populations. In conclusion, these populations could be pooled together in order to create one “Colombian-Mestizo” database for forensic use.

Keywords: Forensic science, Y-Chromosome, DNA typing, STR, Haplotype, DYS19, DYS385a, DYS385b, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS438, DYS439, DYS437, DYS448, DYS456, DYS458, DYS635, GATA-H4, Colombia, Population genetics

To access this article, please choose from the options below

Login to an existing account or Register a new account.

  • Purchase this article for 31.50 USD (You must login/register to purchase this article)

    Online access for 24 hours. The PDF version can be downloaded as your permanent record.

  • Subscribe to this title

    Get unlimited online access to this article and all other articles in this title 24/7 for one year.

  • Claim access now

    For current subscribers with Society Membership or Account Number.

  • Visit SciVerse ScienceDirect to see if you have access via your institution.
 

PII: S1752-928X(08)00233-3

doi:10.1016/j.jflm.2008.12.002

Journal of Forensic and Legal Medicine
Volume 16, Issue 4 , Pages 204-211, May 2009

Article Tools