Journal of Forensic and Legal Medicine
Volume 15, Issue 5 , Pages 329-334 , July 2008

Systematic evaluation of sensitivity and specificity of sibship determination by using 15 STR loci

  • Chang En Pu, MS ((Scientist Specialist and Section Chief))

      Affiliations

    • Forensic DNA Section, Scientific and Technical Research Center, Ministry Justice Investigation Bureau, No. 74 Chun_hya Road, Hsin-tien, Taipei County 231, Taiwan
    • Corresponding Author InformationCorresponding author. Tel.: +886 2 29112241x3740; fax: +886 2 291 38599.
    • ,
  • Adrian Linacre, PhD ((Senior Lecturer))

      Affiliations

    • Centre for Forensic Science, Department of Pure and Applied Chemistry, University of Strathclyde, Glasgow, UK

Received 17 June 2007 ,Revised 30 August 2007 ,Accepted 31 December 2007.

References 

  1. Wenk RE, Traver M, Chiafari FA. Determination of sibship in any two persons. Transfusion. 1996;36:259–262
  2. Tzeng CH, Lyou JY, Chen YR, Hu HY, Lin JS, Wang SY, et al. Determination of sibship by PCR-amplified short tandem repeat analysis in Taiwan. Transfusion. 2000;40:840–845
  3. Wenk RE, Chiafari FA. Distinguishing full siblings from half-siblings in limited pedigrees. Transfusion. 2000;40:1148–1149
  4. Gaytmenn R, Hildebrand DP, Sweet D, Pretty IA. Determination of the sensitivity and specificity of sibship calculations using AmpFISTR profiler plus. Int J Legal Med. 2002;116:161–164
  5. Henke J, Henke L. Which short tandem repeat polymorphisms are required for identification? Lessons from complicated kinship cases. Croat Med J. 2005;46(4):593–597
  6. Thomson JA, Ayres KL, Pilotti V, Barrett MN, Walker JIH, Debenham PG. Analysis of disputed single-parent/child and sibling relationships using 16 STR loci. Int J Legal Med. 2000;115:128–134
  7. Reid TM, Wolf CA, Kraemer CM, Lee SC, Baird ML, Lee RF. Specificity of sibship determination using the ABI identifiler multiplex system. J Forensic Sci. 2004;49:1–3
  8. Giroti RI, Verma S, Singh K, Malik R, Talwar I. A gray zone approach for evaluation of 15 short tandem repeat loci in sibship analysis: a pilot study in Indian subjects. J Clin Forensic Med. 2006;
  9. Short tandom repeat DNA internet database. http://www.cstl.nist.gov/div831/strbase.
  10. Butler JM. Kinship and parentage testing. In:  Butler JM editors. Forensic DNA typing. MA, USA: Elsevier Academic Press; 2005;p. 529–537
  11. Find ‘best’ cut-offs for maximizing sensitivity/specificity. Available from: http://www.natureserve.org/visitLocal/conftraining/edmworkshop/rochelp.pdf. 2007.
  12. Zou KH, Wells WM, Kikinis R, Warfield SK. Three validation metrics for automated probabilistic image segmentation of brain tumors. Statist Med. 2004;23:1259–1282
  13. Kirkwood BR, Sterne JAC. Measurement error: assessment and implications. In:  Kirkwood BR,  Sterne JAC editor. Medical statistics. MA, USA: Blackwell Publishing; 2003;p. 429–446
  14. AABB, 2002 parentage testing annual report. MD, USA: American Association of Blood Banks; 2007. http://www.aabb.org/Documents/Accreditation/Parentage_Testing_Accreditation_Program/ptannrpt02.pdf.

PII: S1752-928X(08)00008-5

doi: 10.1016/j.jflm.2007.12.018

Journal of Forensic and Legal Medicine
Volume 15, Issue 5 , Pages 329-334 , July 2008

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