Journal of Forensic and Legal Medicine
Volume 15, Issue 5 , Pages 312-317 , July 2008

Biochemical blood markers and sampling sites in forensic autopsy

  • Koichi Uemura, MD, PhD

      Affiliations

    • Department of Forensic Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan
    • Section of Forensic Medicine, Department of International Health Development, Division of Public Health, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan
    • Corresponding Author InformationCorresponding author. Address: Section of Forensic Medicine, Department of International Health Development, Division of Public Health, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan. Tel.: +81 3 5803 5197; fax: +81 3 5803 0128.
  • ,
  • Kaori Shintani-Ishida, MSc

      Affiliations

    • Department of Forensic Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan
  • ,
  • Kanju Saka, BSc

      Affiliations

    • Department of Forensic Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan
  • ,
  • Makoto Nakajima, MVet

      Affiliations

    • Department of Forensic Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan
  • ,
  • Hiroshi Ikegaya, MD, PhD

      Affiliations

    • National Research Institute of Police Science, 6-3-1, Kashiwanoha, Kashiwa-city, Chiba 277-0880, Japan
  • ,
  • Yousuke Kikuchi, MD

      Affiliations

    • Department of Forensic Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan
  • ,
  • Ken-ichi Yoshida, MD, PhD

      Affiliations

    • Department of Forensic Medicine, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan

Received 28 September 2006 ,Revised 24 November 2007 ,Accepted 13 December 2007.

References 

  1. Coe JI. Postmortem chemistry update. Am J Forensic Med Pathol. 1993;14:91–117
  2. Tsuji A, Ikeda N, Kojimahara M, Takeichi S. Forensic application of biochemical blood analysis – experimental studies of postmortem changes of value in cadaveric blood. Res Pract Forensic Med. 1993;36:97–103[in Japanese]
  3. Hart AP, Zumwalt RE, Dasgupta A. Postmortem lipid levels for the analysis of risk factors of sudden death. Usefulness of Ektachem and Monarch analyzers. Am J Forensic Med Pathol. 1997;18:354–359
  4. Tsuji A, Ikeda N, Kojimahara M, Takeichi S. Forensic application of biochemical blood analysis – normal range of cadaveric blood. Res Pract Forensic Med. 1992;35:105–108[in Japanese]
  5. Uhlin-Hansen L. C-reactive protein (CRP), a comparison of pre- and post-mortem blood levels. Forensic Sci Int. 2001;124:32–35
  6. Fujita MQ, Zhu BL, Ishida K, Quan L, Oritani S, Maeda H. Serum C-reactive protein levels in postmortem blood – an analysis with special reference to the cause of death and survival time. Forensic Sci Int. 2002;130:160–166
  7. Tamaki K, Katsumata Y. Enzyme-linked immunoabsorbent assay for plasma thyroglobulin following compression of the neck. Forensic Sci Int. 1990;44:193–201
  8. Ansari MQ, Zamora JL, Lipscomb MF. Postmortem diagnosis of acute anaphylaxis by serum tryptase analysis. Am J Clin Pathol. 1993;99:101–103
  9. Akane A, Shiono H, Matsubara K, Tanabe K, Nakamura H, Hasegawa M, et al. Analysis of glycated albumin in postmortem blood samples as the diagnostic parameters of diabetes mellitus. Jpn J Legal Med. 1992;46:237–243
  10. Kuroda N. Determination of glycated hemoglobins of cadaveric blood: a study involving the use of affinity chromatography with m-amino phenyl boronic acid. Jpn J Legal Med. 1990;44:115–125
  11. Khuu HM, Robinson CA, Brissie RM, Konrad RJ. Postmortem diagnosis of unsuspected diabetes mellitus established by determination of decedent’s hemoglobin A1c level. J Forensic Sci. 1999;44:643–646
  12. Winecker RE, Hammett-Stabler CA, Chapman JF, Ropero-Miller JD. HbA1c as a postmortem tool to identify glycemic control. J Forensic Sci. 2002;47:1373–1379
  13. Goullé J-P, Lacroix C, Bouige D. Glycated hemoglobin: a useful post-mortem reference marker in determining diabetes. Forensic Sci Int. 2002;128:44–49
  14. Valenzuela A. Postmortem diagnosis of diabetes mellitus. Quantitation of fructosamine and glycated hemoglobin. Forensic Sci Int. 1988;38:203–268
  15. Zhu BL, Ishida K, Quan L, Taniguchi M, Oritani S, Li DR, et al. Postmortem serum uric acid and creatinine levels in relation to the causes of death. Forensic Sci Int. 2002;125:59–66

PII: S1752-928X(07)00194-1

doi: 10.1016/j.jflm.2007.12.003

Journal of Forensic and Legal Medicine
Volume 15, Issue 5 , Pages 312-317 , July 2008