Journal of Forensic and Legal Medicine
Volume 14, Issue 8 , Pages 461-470 , November 2007

Pulmonary intra-alveolar hemorrhage in SIDS and suffocation

  • Henry F. Krous, MD

      Affiliations

    • Department of Pathology, Rady Children’s Hospital, San Diego, CA, USA
    • Departments of Pathology and Pediatrics, University of California, San Diego School of Medicine, La Jolla, CA, USA
    • Corresponding Author InformationCorresponding author. Address: Department of Pathology, Rady Children’s Hospital, San Diego, CA, USA. Tel.: +858 966 5944; fax: +858 966 8087.
    • ,
  • Amy E. Chadwick, BA

      Affiliations

    • Department of Pathology, Rady Children’s Hospital, San Diego, CA, USA
    • ,
  • Elisabeth A. Haas, MPH

      Affiliations

    • Department of Pathology, Rady Children’s Hospital, San Diego, CA, USA
    • ,
  • Christina Stanley, MD

      Affiliations

    • Office of the Medical Examiner, County of San Diego, CA, USA

Received 20 July 2006 ,Revised 12 September 2006 ,Accepted 24 October 2006.

References 

  1. Krous HF, Beckwith JB, Byard RW, et al. Sudden infant death syndrome and unclassified sudden infant deaths: a definitional and diagnostic approach. Pediatrics. 2004;114:234–238
  2. Malloy MH. Trends in postneonatal aspiration deaths and reclassification of sudden infant death syndrome: impact of the “Back to Sleep” program. Pediatrics. 2002;109:661–665
  3. Byard RW. Sudden death in infancy, childhood and adolescence. 2nd ed.. Cambridge: Cambridge University Press; 2004;
  4. Bajanowski T, Vennemann M, Bohnert M, Rauch E, Brinkmann B, Mitchell EA. Unnatural causes of sudden unexpected deaths initially thought to be sudden infant death syndrome. Int J Legal Med. 2005;119:213–216
  5. Bohnert M, Grosse Perdekamp M, Pollak S. Three subsequent infanticides covered up as SIDS. Int J Legal Med. 2005;119:31–34
  6. Meadow R. Unnatural sudden infant death. Arch Dis Child. 1999;80:7–14
  7. Perrot LJ, Nawojczyk S. Nonnatural death masquerading as SIDS (sudden infant death syndrome). Am J Forensic Med Pathol. 1988;9:105–111
  8. Becroft DM, Lockett BK. Intra-alveolar pulmonary siderophages in sudden infant death: a marker for previous imposed suffocation. Pathology. 1997;29:60–63
  9. Becroft DM, Thompson JM, Mitchell EA. Nasal and intrapulmonary haemorrhage in sudden infant death syndrome. Arch Dis Child. 2001;85:116–120
  10. Hanzlick R. Pulmonary hemorrhage in deceased infants: baseline data for further study of infant mortality. Am J Forensic Med Pathol. 2001;22:188–192
  11. Hanzlick R, Delaney K. Pulmonary hemosiderin in deceased infants: baseline data for further study of infant mortality. Am J Forensic Med Pathol. 2000;21:319–322
  12. Schluckebier DA, Cool CD, Henry TE, Martin A, Wahe JW. Pulmonary siderophages and unexpected infant death. Am J Forensic Med Pathol. 2002;23:360–363
  13. Yukawa N, Carter N, Rutty G, Green MA. Intra-alveolar haemorrhage in sudden infant death syndrome: a cause for concern?. J Clin Pathol. 1999;52:581–587
  14. Krous HF, Wixom C, Chadwick AE, Haas EA, Silva PD, Stanley C. Pulmonary intra-alveolar siderophages in SIDS and suffocation: A San Diego SIDS/SUDC Research Project Report. Pediatr Dev Pathol. 2006;9:103–114
  15. Krous HF, Haas EA, Manning JM, et al. Child protective services referrals in cases of sudden infant death: a 10-year, population-based analysis in San Diego County, California. Child Maltreat. 2006;11:247–256
  16. Krous HF, Nadeau JM, Byard RW, Blackbourne BD. Oronasal blood in sudden infant death. Am J Forensic Med Pathol. 2001;22:346–351
  17. Valdes-Dapena M. The sudden infant death syndrome: pathologic findings. Clin Perinatol. 1992;19:701–716
  18. Berry PJ. Intra-alveolar haemorrhage in sudden infant death syndrome: a cause for concern?. J Clin Pathol. 1999;52:553–554[editorial; comment]
  19. Potter S, Berry PJ, Fleming P. Pulmonary haemorrhage in sudden unexpected death in infancy. Pediatr Dev Pathol. 1999;2:394–395
  20. Southall DP, Plunkett MC, Banks MW, Falkov AF, Samuels MP. Covert video recordings of life-threatening child abuse: lessons for child protection. Pediatrics. 1997;100:735–760
  21. Farber JP, Catron AC, Krous HF. Pulmonary petechiae: ventilatory–circulatory interactions. Pediatr Res. 1983;17:230–233
  22. Krous HF. The microscopic distribution of intrathoracic petechiae in sudden infant death syndrome. Arch Pathol Lab Med. 1984;108:77–79
  23. Krous HF, Jordan J. A necropsy study of distribution of petechiae in non-sudden infant death syndrome. Arch Pathol Lab Med. 1984;108:75–76
  24. Mitchell EA, Brunt JM, Everard C. Reduction in mortality from sudden infant death syndrome in New Zealand:1986–92. Arch Dis Child. 1994;70:291–294
  25. Taylor JA, Krieger JW, Reay DT, Davis RL, Harruff R, Cheney LK. Prone sleep position and the sudden infant death syndrome in King County, Washington: a case-control study. J Pediatr. 1996;128:626–630
  26. Hauck FR. Changing epidemiology. In:  Byard RW,  Krous HF editor. Sudden infant death syndrome: problems, progress & possibilities. London: Arnold; 2001;p. 31–57
  27. Hauck FR, Herman SM, Donovan M, et al. Sleep environment and the risk of sudden infant death syndrome in an urban population: the Chicago Infant Mortality Study. Pediatrics. 2003;111:1207–1214
  28. Kemp JS, Unger B, Wilkins D, et al. Unsafe sleep practices and an analysis of bedsharing among infants dying suddenly and unexpectedly: results of a four-year, population-based, death-scene investigation study of sudden infant death syndrome and related deaths. Pediatrics. 2000;106:E41
  29. Hauck F. Bedsharing: review of epidemiologic data examing links to SIDS. Paper presented at: infant sleep environment and SIDS risk conference; January 9–10, 1997; Bethesda, MD.
  30. Iyasu S, Rowley D, Hanzlick R. Guidelines for death scene investigation of sudden, unexplained infant deaths: recommendations of the interagency panel on sudden infant death syndrome. MMWR Morb Mortal Wkly Rep. 1996;45:1–6
  31. Krous HF, Byard RW. International standardized autopsy protocol for sudden unexpected infant death. Appendix I. In:  Byard RW,  Krous HF editor. Sudden infant death syndrome: problems, progress and possibilities. London: Arnold; 2001;p. 319–333

PII: S1353-1131(06)00217-3

doi: 10.1016/j.jcfm.2006.10.004

Journal of Forensic and Legal Medicine
Volume 14, Issue 8 , Pages 461-470 , November 2007

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